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学习笔记:基于＂5R＂原则的我国儿童百日咳抗菌治疗决策探讨

  • 2026-04-17 16:37:34
学习笔记:基于＂5R＂原则的我国儿童百日咳抗菌治疗决策探讨
5R原则：是指从患者、药物、时机和疗程、剂量、给药途径等五个方面的正确选择。
正确的患者：选择百日咳病程21天内使用有效的抗生素治疗，超过21天后使用抗生素的意义不大。
正确的药物：首选TMP-SMZ治疗。
正确的时机和疗程：在百日咳潜伏期、卡他期或发作期早期给予有效抗菌药物，可防止发病或发生剧烈的咳嗽，降低疾病严重程度 。TMP-SMZ治疗百日咳的推荐疗程14 d。
正确剂量：2月龄以上儿童，以磺胺甲恶唑（SMZ)20mg/kg.次计算，2次/天，疗程14天。
正确的给药途径：口服用药，只有在频繁呕吐影响药物吸收的情况下采用胃肠外给药方式。
看图说病：百日咳

〔免责声明〕

本文仅作健康科普，科普内容不能代替医生诊治意见，也不能替代医院的检查和治疗。如有相关疾病，请及时去正规医疗机构就诊，谨遵医嘱！
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  1. CONNECT:[ UseTime:0.000508s ] mysql:host=127.0.0.1;port=3306;dbname=no_67808;charset=utf8mb4
  2. SHOW FULL COLUMNS FROM `fenlei` [ RunTime:0.000585s ]
  3. SELECT * FROM `fenlei` WHERE `fid` = 0 [ RunTime:0.001108s ]
  4. SELECT * FROM `fenlei` WHERE `fid` = 63 [ RunTime:0.001359s ]
  5. SHOW FULL COLUMNS FROM `set` [ RunTime:0.000502s ]
  6. SELECT * FROM `set` [ RunTime:0.000211s ]
  7. SHOW FULL COLUMNS FROM `article` [ RunTime:0.000605s ]
  8. SELECT * FROM `article` WHERE `id` = 481008 LIMIT 1 [ RunTime:0.001323s ]
  9. UPDATE `article` SET `lasttime` = 1776429150 WHERE `id` = 481008 [ RunTime:0.003269s ]
  10. SELECT * FROM `fenlei` WHERE `id` = 65 LIMIT 1 [ RunTime:0.000282s ]
  11. SELECT * FROM `article` WHERE `id` < 481008 ORDER BY `id` DESC LIMIT 1 [ RunTime:0.000431s ]
  12. SELECT * FROM `article` WHERE `id` > 481008 ORDER BY `id` ASC LIMIT 1 [ RunTime:0.002339s ]
  13. SELECT * FROM `article` WHERE `id` < 481008 ORDER BY `id` DESC LIMIT 10 [ RunTime:0.002610s ]
  14. SELECT * FROM `article` WHERE `id` < 481008 ORDER BY `id` DESC LIMIT 10,10 [ RunTime:0.003438s ]
  15. SELECT * FROM `article` WHERE `id` < 481008 ORDER BY `id` DESC LIMIT 20,10 [ RunTime:0.002162s ]
0.100542s