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血脂目标管理 | 学习笔记

  • 2026-02-09 11:20:52
血脂目标管理 | 学习笔记

血脂目标管理 | 学习笔记

💡 核心治疗原则
调脂药物治疗时，推荐将降低LDL-C作为主要治疗目标，依据ASCVD风险等级设定不同目标值。非HDL-C是次要干预靶点，与ASCVD残余风险增高有关。
关键特征：分层管理、数值精确、双靶点干预

📋 风险分层与目标值
合并ASCVD的患者：LDL-C <1.4 mmol/L
ASCVD高危患者（年龄**≥40岁**，或20~39岁且合并**≥3种危险因素**或合并靶器官损害）：LDL-C <1.8 mmol/L
其余T2DM患者：LDL-C <2.6 mmol/L

✓ 临床管理路径 评估ASCVD风险等级 → 确定患者所属分层 → 设定对应LDL-C目标值 → 计算非HDL-C目标值（LDL-C目标值 + 0.8 mmol/L）→ 选择调脂方案 → 定期监测双靶点达标情况

⚠️ 关键警示与注意事项 [LDL-C目标值不可更改] ：必须严格遵循 <1.4/<1.8/<2.6 mmol/L 的数值标准
[非HDL-C计算] ：目标值=相应LDL-C目标值 +0.8 mmol/L，不可直接套用固定数值
[高危识别] ：20~39岁患者需满足≥3种危险因素或靶器官损害才属高危
[首要目标] ：LDL-C是首要干预靶点，非HDL-C管理不可优先于LDL-C

📌 标签
#内分泌科 #糖尿病治疗 #血脂管理 #ASCVD #临床指南 #住院医师

👉 获取【PPT】请参考以下链接：
 中国糖尿病防治指南(2024 版)-第十三章|学习笔记PPT

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  1. CONNECT:[ UseTime:0.001075s ] mysql:host=127.0.0.1;port=3306;dbname=no_67808;charset=utf8mb4
  2. SHOW FULL COLUMNS FROM `fenlei` [ RunTime:0.001667s ]
  3. SELECT * FROM `fenlei` WHERE `fid` = 0 [ RunTime:0.004163s ]
  4. SELECT * FROM `fenlei` WHERE `fid` = 63 [ RunTime:0.003077s ]
  5. SHOW FULL COLUMNS FROM `set` [ RunTime:0.001429s ]
  6. SELECT * FROM `set` [ RunTime:0.007827s ]
  7. SHOW FULL COLUMNS FROM `article` [ RunTime:0.001500s ]
  8. SELECT * FROM `article` WHERE `id` = 462640 LIMIT 1 [ RunTime:0.004417s ]
  9. UPDATE `article` SET `lasttime` = 1770730525 WHERE `id` = 462640 [ RunTime:0.021816s ]
  10. SELECT * FROM `fenlei` WHERE `id` = 65 LIMIT 1 [ RunTime:0.001134s ]
  11. SELECT * FROM `article` WHERE `id` < 462640 ORDER BY `id` DESC LIMIT 1 [ RunTime:0.013494s ]
  12. SELECT * FROM `article` WHERE `id` > 462640 ORDER BY `id` ASC LIMIT 1 [ RunTime:0.004008s ]
  13. SELECT * FROM `article` WHERE `id` < 462640 ORDER BY `id` DESC LIMIT 10 [ RunTime:0.029017s ]
  14. SELECT * FROM `article` WHERE `id` < 462640 ORDER BY `id` DESC LIMIT 10,10 [ RunTime:0.026443s ]
  15. SELECT * FROM `article` WHERE `id` < 462640 ORDER BY `id` DESC LIMIT 20,10 [ RunTime:0.018688s ]
0.288671s