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西药综合 学习笔记 倒计时160天

  • 2026-05-24 21:49:53
西药综合 学习笔记 倒计时160天

西药综合 学习笔记 倒计时160天

第十一章 消化系统常见疾病
第三节 溃疡性结肠炎
第四节 慢性病毒性肝炎

一、溃疡性结肠炎相关

1. 美沙拉秦的药物特点

① 通过在肠道内发挥局部黏膜抗炎作用起效，而不是全身作用。
② 常用前体药物或缓、控释制剂以便于肠道释放。

2. 美沙拉秦的三个前体药物

- 奥沙拉秦：进餐时服用
​
- 巴柳氮：（无额外标注）
​
- 柳氮磺吡啶：进餐时服用；需补充叶酸；可降低精子数量和活力

3. 溃疡性结肠炎的治疗思路

首选氨基水杨酸制剂；次选糖皮质激素；重症可加用免疫抑制剂或生物制剂。

 

二、病毒性肝炎相关

1. 乙型病毒性肝炎

抗病毒药物分类：
① 核苷酸类似物（NAs）：首选，常用药物中首选恩替卡韦和替诺福韦
② 干扰素α
③ 妊娠女性：选用富马酸替诺福韦酯

2. 丙型病毒性肝炎

抗病毒药物分类：
① 直接作用抗病毒药物：索磷布韦/维帕他韦、格卡瑞韦/哌仑他韦、索磷布韦/维帕他韦/伏西瑞韦
② 干扰素α
③ 利巴韦林
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      1. CONNECT:[ UseTime:0.001202s ] mysql:host=127.0.0.1;port=3306;dbname=no_67808;charset=utf8mb4
      2. SHOW FULL COLUMNS FROM `fenlei` [ RunTime:0.001547s ]
      3. SELECT * FROM `fenlei` WHERE `fid` = 0 [ RunTime:0.000754s ]
      4. SELECT * FROM `fenlei` WHERE `fid` = 63 [ RunTime:0.000656s ]
      5. SHOW FULL COLUMNS FROM `set` [ RunTime:0.001292s ]
      6. SELECT * FROM `set` [ RunTime:0.000544s ]
      7. SHOW FULL COLUMNS FROM `article` [ RunTime:0.001517s ]
      8. SELECT * FROM `article` WHERE `id` = 490517 LIMIT 1 [ RunTime:0.001021s ]
      9. UPDATE `article` SET `lasttime` = 1779656425 WHERE `id` = 490517 [ RunTime:0.053020s ]
      10. SELECT * FROM `fenlei` WHERE `id` = 65 LIMIT 1 [ RunTime:0.040156s ]
      11. SELECT * FROM `article` WHERE `id` < 490517 ORDER BY `id` DESC LIMIT 1 [ RunTime:0.006858s ]
      12. SELECT * FROM `article` WHERE `id` > 490517 ORDER BY `id` ASC LIMIT 1 [ RunTime:0.001549s ]
      13. SELECT * FROM `article` WHERE `id` < 490517 ORDER BY `id` DESC LIMIT 10 [ RunTime:0.001884s ]
      14. SELECT * FROM `article` WHERE `id` < 490517 ORDER BY `id` DESC LIMIT 10,10 [ RunTime:0.001886s ]
      15. SELECT * FROM `article` WHERE `id` < 490517 ORDER BY `id` DESC LIMIT 20,10 [ RunTime:0.014525s ]
      0.306457s